The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery

The state of antileishmanial chemotherapy is strongly compromised by the emergence of drug-resistant Leishmania. The evolution of drug-resistant phenotypes has been linked to the parasites’ intrinsic genome instability, with frequent gene and chromosome amplifications causing fitness gains that are...

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Detalles Bibliográficos
Autores principales: Lamotte, Suzanne, Späth, Gerald F., Rachidi, Najma, Prina, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464532/
https://www.ncbi.nlm.nih.gov/pubmed/28594938
http://dx.doi.org/10.1371/journal.pntd.0005480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464532/
https://www.ncbi.nlm.nih.gov/pubmed/28594938
http://dx.doi.org/10.1371/journal.pntd.0005480

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