Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

BACKGROUND: Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to assess causality, may help to identify the metabolic drivers of lung cancer....

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Detalles Bibliográficos
Autores principales: Carreras-Torres, Robert, Johansson, Mattias, Haycock, Philip C., Wade, Kaitlin H., Relton, Caroline L., Martin, Richard M., Davey Smith, George, Albanes, Demetrius, Aldrich, Melinda C., Andrew, Angeline, Arnold, Susanne M., Bickeböller, Heike, Bojesen, Stig E., Brunnström, Hans, Manjer, Jonas, Brüske, Irene, Caporaso, Neil E., Chen, Chu, Christiani, David C., Christian, W. Jay, Doherty, Jennifer A., Duell, Eric J., Field, John K., Davies, Michael P. A., Marcus, Michael W., Goodman, Gary E., Grankvist, Kjell, Haugen, Aage, Hong, Yun-Chul, Kiemeney, Lambertus A., van der Heijden, Erik H. F. M., Kraft, Peter, Johansson, Mikael B., Lam, Stephen, Landi, Maria Teresa, Lazarus, Philip, Le Marchand, Loïc, Liu, Geoffrey, Melander, Olle, Park, Sungshim L., Rennert, Gad, Risch, Angela, Haura, Eric B., Scelo, Ghislaine, Zaridze, David, Mukeriya, Anush, Savić, Milan, Lissowska, Jolanta, Swiatkowska, Beata, Janout, Vladimir, Holcatova, Ivana, Mates, Dana, Schabath, Matthew B., Shen, Hongbing, Tardon, Adonina, Teare, M Dawn, Woll, Penella, Tsao, Ming-Sound, Wu, Xifeng, Yuan, Jian-Min, Hung, Rayjean J., Amos, Christopher I., McKay, James, Brennan, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464539/
https://www.ncbi.nlm.nih.gov/pubmed/28594918
http://dx.doi.org/10.1371/journal.pone.0177875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464539/
https://www.ncbi.nlm.nih.gov/pubmed/28594918
http://dx.doi.org/10.1371/journal.pone.0177875

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