Systematic genomic and translational efficiency studies of uveal melanoma

To further our understanding of the somatic genetic basis of uveal melanoma, we sequenced the protein-coding regions of 52 primary tumors and 3 liver metastases together with paired normal DNA. Known recurrent mutations were identified in GNAQ, GNA11, BAP1, EIF1AX, and SF3B1. The role of mutated EIF...

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Detalles Bibliográficos
Autores principales: Johnson, Chelsea Place, Kim, Ivana K., Esmaeli, Bita, Amin-Mansour, Ali, Treacy, Daniel J., Carter, Scott L., Hodis, Eran, Wagle, Nikhil, Seepo, Sara, Yu, Xiaoxing, Lane, Anne Marie, Gragoudas, Evangelos S., Vazquez, Francisca, Nickerson, Elizabeth, Cibulskis, Kristian, McKenna, Aaron, Gabriel, Stacey B., Getz, Gad, Van Allen, Eliezer M., ‘t Hoen, Peter A. C., Garraway, Levi A., Woodman, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464544/
https://www.ncbi.nlm.nih.gov/pubmed/28594900
http://dx.doi.org/10.1371/journal.pone.0178189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464544/
https://www.ncbi.nlm.nih.gov/pubmed/28594900
http://dx.doi.org/10.1371/journal.pone.0178189

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