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Conophylline inhibits non-alcoholic steatohepatitis in mice

Conophylline (CnP), a vinca alkaloid extracted from the leaves of the tropical plant Ervatamia microphylla, attenuates hepatic fibrosis in mice. However, little is known about whether CnP inhibits steatosis, inflammation, and fibrosis in non-alcoholic steatohepatitis (NASH) in mice. A methionine-cho...

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Detalles Bibliográficos
Autores principales: Nakade, Yukiomi, Sakamoto, Kazumasa, Yamauchi, Taeko, Inoue, Tadahisa, Kobayashi, Yuji, Yamamoto, Takaya, Ishii, Norimitsu, Ohashi, Tomohiko, Sumida, Yoshio, Ito, Kiyoaki, Nakao, Haruhisa, Fukuzawa, Yoshitaka, Umezawa, Kazuo, Yoneda, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464552/
https://www.ncbi.nlm.nih.gov/pubmed/28594915
http://dx.doi.org/10.1371/journal.pone.0178436