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Study of structural stability and damaging effect on membrane for four Aβ42 dimers

Increasing evidence shows that Aβ oligomers are key pathogenic molecules in Alzheimer’s disease. Among Aβ oligomers, dimer is the smallest aggregate and toxic unit. Therefore, understanding its structural and dynamic properties is quite useful to prevent the formation and toxicity of the Aβ oligomer...

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Detalles Bibliográficos
Autores principales: Feng, Wei, Lei, Huimin, Si, Jiarui, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464659/
https://www.ncbi.nlm.nih.gov/pubmed/28594887
http://dx.doi.org/10.1371/journal.pone.0179147