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ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway
Elevated intraocular pressure is the most prevalent and only treatable risk factor for glaucoma, a degenerative disease of the optic nerve. While treatment options to slow disease progression are available, all current therapeutic and surgical treatments have unwanted side effects or limited efficac...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464668/ https://www.ncbi.nlm.nih.gov/pubmed/28594895 http://dx.doi.org/10.1371/journal.pone.0179345 |