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Study of the cytotoxic/toxic potential of the novel anticancer selenodiazoloquinolone on fibroblast cells and 3D skin model

The new synthetically prepared quinolone derivative 7-ethyl 9-ethyl-6-oxo-6,9-dihydro[1,2,5]selenadiazolo [3,4-h]quinoline-7-carboxylate (E2h) showed in our previous study cytotoxic effects towards tumor cells and immunomodulatory activities on RAW 264.7 cell line murine macrophages. E2h may have a...

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Detalles Bibliográficos
Autores principales: Jantová, Soňa, Topoľská, Dominika, Janošková, Michaela, Pánik, Miroslav, Milata, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464683/
https://www.ncbi.nlm.nih.gov/pubmed/28652854
http://dx.doi.org/10.1515/intox-2016-0014