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Quantification and Assessment of the Chemical Form of Residual Gadolinium in the Brain After Repeated Administration of Gadolinium-Based Contrast Agents: Comparative Study in Rats

OBJECTIVE: Multiple clinical and preclinical studies have reported a signal intensity increase and the presence of gadolinium (Gd) in the brain after repeated administration of Gd-based contrast agents (GBCAs). This bioanalytical study in rat brain tissue was initiated to investigate whether the res...

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Detalles Bibliográficos
Autores principales: Frenzel, Thomas, Apte, Chirag, Jost, Gregor, Schöckel, Laura, Lohrke, Jessica, Pietsch, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464750/
https://www.ncbi.nlm.nih.gov/pubmed/28125438
http://dx.doi.org/10.1097/RLI.0000000000000352