ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate

Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved. We probed the ER retention process using the proteostasis regulator 4-phenylbutyrate...

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Detalles Bibliográficos
Autores principales: Ma, Wenfu, Goldberg, Elena, Goldberg, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464768/
https://www.ncbi.nlm.nih.gov/pubmed/28594326
http://dx.doi.org/10.7554/eLife.26624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464768/
https://www.ncbi.nlm.nih.gov/pubmed/28594326
http://dx.doi.org/10.7554/eLife.26624

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