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PreImplantation factor (PIF) protects cultured embryos against oxidative stress: relevance for recurrent pregnancy loss (RPL) therapy

Recurrent pregnancy loss (RPL) affects 2-3% of couples. Despite a detailed work-up, the etiology is frequently undefined, leading to non-targeted therapy. Viable embryos and placentae express PreImplantation Factor (PIF). Maternal circulating PIF regulates systemic immunity and reduces circulating n...

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Detalles Bibliográficos
Autores principales: Goodale, Lindsay F., Hayrabedran, Soren, Todorova, Krassimira, Roussev, Roumen, Ramu, Sivakumar, Stamatkin, Christopher, Coulam, Carolyn B., Barnea, Eytan R., Gilbert, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464799/
https://www.ncbi.nlm.nih.gov/pubmed/28423690
http://dx.doi.org/10.18632/oncotarget.16028