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Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy

Immunotherapy has historically been successful in highly antigenic tumors but has shown limited therapeutic efficacy in non-antigenic tumors such as breast cancers. Our previous studies in autoimmunity have demonstrated that increased antigen load within a tissue enhances immune reactivity against i...

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Detalles Bibliográficos
Autores principales: Jaini, Ritika, Loya, Matthew G., Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464807/
https://www.ncbi.nlm.nih.gov/pubmed/28430646
http://dx.doi.org/10.18632/oncotarget.15812