Cargando…
Immunotherapeutic target expression on breast tumors can be amplified by hormone receptor antagonism: a novel strategy for enhancing efficacy of targeted immunotherapy
Immunotherapy has historically been successful in highly antigenic tumors but has shown limited therapeutic efficacy in non-antigenic tumors such as breast cancers. Our previous studies in autoimmunity have demonstrated that increased antigen load within a tissue enhances immune reactivity against i...
Autores principales: | Jaini, Ritika, Loya, Matthew G., Eng, Charis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464807/ https://www.ncbi.nlm.nih.gov/pubmed/28430646 http://dx.doi.org/10.18632/oncotarget.15812 |
Ejemplares similares
-
Targeted Vaccination against Human α-Lactalbumin for Immunotherapy and Primary Immunoprevention of Triple Negative Breast Cancer
por: Tuohy, Vincent K., et al.
Publicado: (2016) -
CAMKV Is a Candidate Immunotherapeutic Target in MYCN Amplified Neuroblastoma
por: Sussman, Robyn T., et al.
Publicado: (2020) -
Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells
por: Yu, Wanfeng, et al.
Publicado: (2017) -
Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression
por: Jaini, Ritika, et al.
Publicado: (2021) -
Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype
por: Sarn, Nicholas, et al.
Publicado: (2020)