High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

The use of high-dose ascorbate (ASC) for the treatment of human cancer has been attempted several decades ago and has been recently revived by several in vitro and in vivo studies in solid tumors. We tested the cytotoxic effects of ASC, alone or in combination with arsenic trioxide (ATO) in acute my...

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Detalles Bibliográficos
Autores principales: Noguera, Nélida I., Pelosi, Elvira, Angelini, Daniela F., Piredda, Maria Liliana, Guerrera, Gisella, Piras, Eleonora, Battistini, Luca, Massai, Lauretta, Berardi, Anna, Catalano, Gianfranco, Cicconi, Laura, Castelli, Germana, D’Angiò, Agnese, Pasquini, Luca, Graziani, Grazia, Fioritoni, Giuseppe, Voso, Maria Teresa, Mastrangelo, Domenico, Testa, Ugo, Lo-Coco, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464808/
https://www.ncbi.nlm.nih.gov/pubmed/28427227
http://dx.doi.org/10.18632/oncotarget.15925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464808/
https://www.ncbi.nlm.nih.gov/pubmed/28427227
http://dx.doi.org/10.18632/oncotarget.15925

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