Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis

Hexokinases II (HK2) is a hub in the regulation of cancer cell glycolysis. Here we reported deguelin, a natural compound which has been studied in various tumor types, has a profound anti-tumor effect on human non-small cell lung cancer (NSCLC) via directly down-regulating of glycolysis. In NSCLC ce...

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Detalles Bibliográficos
Autores principales: Li, Wei, Gao, Feng, Ma, Xiaoqian, Wang, Ruike, Dong, Xin, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464811/
https://www.ncbi.nlm.nih.gov/pubmed/28427230
http://dx.doi.org/10.18632/oncotarget.15937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464811/
https://www.ncbi.nlm.nih.gov/pubmed/28427230
http://dx.doi.org/10.18632/oncotarget.15937

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