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Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis
Hexokinases II (HK2) is a hub in the regulation of cancer cell glycolysis. Here we reported deguelin, a natural compound which has been studied in various tumor types, has a profound anti-tumor effect on human non-small cell lung cancer (NSCLC) via directly down-regulating of glycolysis. In NSCLC ce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464811/ https://www.ncbi.nlm.nih.gov/pubmed/28427230 http://dx.doi.org/10.18632/oncotarget.15937 |