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EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress
Diabetic nephropathy (DN) is a progressive kidney disease due to glomerular capillary damage in diabetic patients. Endoplasmic reticulum (ER) stress caused by reactive oxygen species (ROS) is associated with DN progression. Epidermal growth factor receptor (EGFR) mediates oxidative stress and damage...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464817/ https://www.ncbi.nlm.nih.gov/pubmed/28427241 http://dx.doi.org/10.18632/oncotarget.15948 |