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EGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress

Diabetic nephropathy (DN) is a progressive kidney disease due to glomerular capillary damage in diabetic patients. Endoplasmic reticulum (ER) stress caused by reactive oxygen species (ROS) is associated with DN progression. Epidermal growth factor receptor (EGFR) mediates oxidative stress and damage...

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Detalles Bibliográficos
Autores principales: Xu, Zheng, Zhao, Yunjie, Zhong, Peng, Wang, Jingying, Weng, Qiaoyou, Qian, Yuanyuan, Han, Jibo, Zou, Chunpeng, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464817/
https://www.ncbi.nlm.nih.gov/pubmed/28427241
http://dx.doi.org/10.18632/oncotarget.15948