Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis

We previously demonstrated that chemopreventive methylselenocysteine (MSC) prevents N-Nitroso-N-methylurea (NMU)-induced mammary carcinogenesis in the susceptible Fischer 344 (F344) rats by enhancing NAD(+)-dependent SIRT1 activity, restoring circadian expression of Period 2 (Per2) and circadian con...

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Detalles Bibliográficos
Autores principales: Fang, Mingzhu, Ohman Strickland, Pamela A., Kang, Hwan-Goo, Zarbl, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464825/
https://www.ncbi.nlm.nih.gov/pubmed/28427145
http://dx.doi.org/10.18632/oncotarget.15678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464825/
https://www.ncbi.nlm.nih.gov/pubmed/28427145
http://dx.doi.org/10.18632/oncotarget.15678

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