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Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis
We previously demonstrated that chemopreventive methylselenocysteine (MSC) prevents N-Nitroso-N-methylurea (NMU)-induced mammary carcinogenesis in the susceptible Fischer 344 (F344) rats by enhancing NAD(+)-dependent SIRT1 activity, restoring circadian expression of Period 2 (Per2) and circadian con...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464825/ https://www.ncbi.nlm.nih.gov/pubmed/28427145 http://dx.doi.org/10.18632/oncotarget.15678 |