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microRNA-200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival

The microRNA-200 (miR-200) family is associated with tumor metastasis and poor patient prognosis. We found that miR-200c/141 cluster overexpression upregulated SerpinB2 in the MDA-MB-231 triple-negative (TN) breast cancer cell line. We observed transcription factor (c-Jun, c-Fos, and FosB) upregulat...

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Detalles Bibliográficos
Autores principales: Jin, Tiefeng, Kim, Hoe Suk, Choi, Sul Ki, Hwang, Eun Hye, Woo, Jisu, Ryu, Han Suk, Kim, Kwangsoo, Moon, Aree, Moon, Woo Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464826/
https://www.ncbi.nlm.nih.gov/pubmed/28427146
http://dx.doi.org/10.18632/oncotarget.15680