Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK

Anti-VEGF therapy has been proven to be effective in the treatment of pathological angiogenesis. However, therapy resistance often occurs, leading to development of alternative approaches. The present study examines if AMPK negatively regulates ALK1-mediated signaling events and associated angiogene...

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Detalles Bibliográficos
Autores principales: Ying, Ying, Ueta, Takashi, Jiang, Shanshan, Lin, Hui, Wang, Yuanyuan, Vavvas, Demetrios, Wen, Rong, Chen, Ye-Guang, Luo, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464828/
https://www.ncbi.nlm.nih.gov/pubmed/28427181
http://dx.doi.org/10.18632/oncotarget.15825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464828/
https://www.ncbi.nlm.nih.gov/pubmed/28427181
http://dx.doi.org/10.18632/oncotarget.15825

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