Combinatorial treatment with polyI:C and anti-IL6 enhances apoptosis and suppresses metastasis of lung cancer cells

Activation of TLR3 stimulates cancer cell apoptosis and triggers secretion of inflammatory cytokines. PolyI:C, a TLR3 agonist, activates immune cells and regresses metastatic lung cancer in vivo. Although polyI:C reportedly kills lung carcinomas, the mechanism remains elusive. Here, we demonstrated...

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Detalles Bibliográficos
Autores principales: Lau, Wai Hoe, Zhu, Xiphias Ge, Ho, Shamaine Wei Ting, Chang, Shu Chun, Ding, Jeak Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464836/
https://www.ncbi.nlm.nih.gov/pubmed/28427199
http://dx.doi.org/10.18632/oncotarget.15862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464836/
https://www.ncbi.nlm.nih.gov/pubmed/28427199
http://dx.doi.org/10.18632/oncotarget.15862

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