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Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival

Glioblastoma (GBM) is the most common malignant brain tumor in adults, with a median survival of 15 months. These poor clinical outcomes have prompted the development of drugs that block neoplastic cancer cell growth; however, non-neoplastic cell-derived signals (chemokines and cytokines) in the tum...

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Detalles Bibliográficos
Autores principales: Pan, Yuan, Smithson, Laura J., Ma, Yu, Hambardzumyan, Dolores, Gutmann, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464843/
https://www.ncbi.nlm.nih.gov/pubmed/28380429
http://dx.doi.org/10.18632/oncotarget.16516