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Enhanced anti-tumor therapeutic efficacy of DNA vaccine by fusing the E7 gene to BAFF in treating human papillomavirus-associated cancer

B-cell-activating factor (BAFF) belongs to the tumor necrosis factor family that not only stimulates B and T cells but also counteracts immune tolerance. BAFF is also a type II membrane protein, which is secreted through the endoplasmic reticulum (ER)–Golgi apparatus pathway. Fusing an antigen to BA...

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Detalles Bibliográficos
Autores principales: Wu, Chao-Chih, Wu, Fang-Cih, Hsu, Yun-Tin, Hsiao, Yu-Chia, Yang, Yuh-Cheng, Chang, C. Allen, Chang, Chih-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464847/
https://www.ncbi.nlm.nih.gov/pubmed/28423693
http://dx.doi.org/10.18632/oncotarget.16032