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Transcriptional regulation of mixed lineage kinase 3 by estrogen and its implication in ER-positive breast cancer pathogenesis

Mixed Lineage Kinase 3 (MLK3), also called as MAP3K11 is a tightly regulated MAP3K member but its cellular function is still not fully understood. Earlier we reported post-translational regulation of MLK3 by estrogen (E2) that inhibited the kinase activity and favored survival of ER(+) breast cancer...

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Detalles Bibliográficos
Autores principales: Viswakarma, Navin, Nair, Rakesh Sathish, Sondarva, Gautam, Das, Subhasis, Ibrahimi, Lucas, Chen, Zhiyong, Sinha, Subhash, Rana, Basabi, Rana, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464859/
https://www.ncbi.nlm.nih.gov/pubmed/28388540
http://dx.doi.org/10.18632/oncotarget.16566