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CD200Fc reduces LPS-induced IL-1β activation in human cervical cancer cells by modulating TLR4-NF-κB and NLRP3 inflammasome pathway

Chronic inflammation plays an important role in tumorigenesis of cervical cancer. CD200Fc, a CD200R1 agonist, has been found to have anti-inflammatory effects in autoimmune diseases and neuro-degeneration. However, the anti-inflammatory effect of CD200Fc on cervical cancer has not yet to be complete...

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Detalles Bibliográficos
Autores principales: He, Aiqin, Shao, Jia, Zhang, Yu, Lu, Hong, Wu, Zhijun, Xu, Yunzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464862/
https://www.ncbi.nlm.nih.gov/pubmed/28402258
http://dx.doi.org/10.18632/oncotarget.16596