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Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1
DNA methyltransferase 1 (DNMT1) is a major epigenetic regulator associated with many biological processes. However, the roles and mechanisms of DNMT1 in skin aging are incompletely understood. Here we explored the role of DNMT1 in human skin fibroblasts senescence and its related regulatory mechanis...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464883/ https://www.ncbi.nlm.nih.gov/pubmed/28380423 http://dx.doi.org/10.18632/oncotarget.16509 |