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Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1

DNA methyltransferase 1 (DNMT1) is a major epigenetic regulator associated with many biological processes. However, the roles and mechanisms of DNMT1 in skin aging are incompletely understood. Here we explored the role of DNMT1 in human skin fibroblasts senescence and its related regulatory mechanis...

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Detalles Bibliográficos
Autores principales: Wang, Ben, Du, Rui, Xiao, Xiao, Deng, Zhi-Li, Jian, Dan, Xie, Hong-Fu, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464883/
https://www.ncbi.nlm.nih.gov/pubmed/28380423
http://dx.doi.org/10.18632/oncotarget.16509

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