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MiR-199a-3p enhances cisplatin sensitivity of cholangiocarcinoma cells by inhibiting mTOR signaling pathway and expression of MDR1

Several studies have reported reduced miRNA-199a-3p (miR-199a-3p) in different human malignancies, however, little is known about miR-199a-3p in cholangiocarcinoma cells. In this study, we demonstrate the essential role and mechanism of miR-199a-3p in regulating cisplatin sensitivity in cholangiocar...

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Detalles Bibliográficos
Autores principales: Li, Qiang, Xia, Xuefeng, Ji, Jie, Ma, Jianghui, Tao, Liang, Mo, Linjun, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464895/
https://www.ncbi.nlm.nih.gov/pubmed/28422725
http://dx.doi.org/10.18632/oncotarget.16834