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Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats

The pathogenesis of hyperuricemia-induced chronic kidney disease is largely unknown. In this study, we investigated whether extracellular signal–regulated kinases1/2 (ERK1/2) would contribute to the development of hyperuricemic nephropathy (HN). In a rat model of HN induced by feeding mixture of ade...

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Detalles Bibliográficos
Autores principales:	Liu, Na, Xu, Liuqing, Shi, Yingfeng, Fang, Lu, Gu, Hongwei, Wang, Hongrui, Ding, Xiaoqiang, Zhuang, Shougang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464913/ https://www.ncbi.nlm.nih.gov/pubmed/28442634 http://dx.doi.org/10.18632/oncotarget.16995

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