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Drug Discovery Targeting Bromodomain-Containing Protein 4

[Image: see text] BRD4, the most extensively studied member of the BET family, is an epigenetic regulator that localizes to DNA via binding to acetylated histones and controls the expression of therapeutically important gene regulatory networks through the recruitment of transcription factors to for...

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Detalles Bibliográficos
Autores principales: Liu, Zhiqing, Wang, Pingyuan, Chen, Haiying, Wold, Eric A., Tian, Bing, Brasier, Allan R., Zhou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464988/
https://www.ncbi.nlm.nih.gov/pubmed/28195723
http://dx.doi.org/10.1021/acs.jmedchem.6b01761