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Tetraploid embryonic stem cells can contribute to the development of chimeric fetuses and chimeric extraembryonic tissues

Our study examined the in vivo chimeric and survival capacities of chimeras created by injecting tetraploid embryonic stem cells (ESCs) expressing green fluorescent protein (GFP) into diploid embryos. At 3.5 days post-coitum (dpc) and 4.5 dpc, the tetraploid ESCs were able to contribute to the inner...

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Detalles Bibliográficos
Autores principales: Wen, Bingqiang, Li, Ruiqi, Cheng, Keren, Li, Enhong, Zhang, Shaopeng, Xiang, Jinzhu, Wang, Yanliang, Han, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465063/
https://www.ncbi.nlm.nih.gov/pubmed/28596585
http://dx.doi.org/10.1038/s41598-017-02783-0