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miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation

Molecular mechanisms regulating preterm birth (PTB)-associated cervical remodeling remain unclear. Prior work demonstrated an altered miRNA profile, with significant increases in miR-143 and miR-145, in cervical cells of women destined to have a PTB. The study objective was to determine the effect o...

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Detalles Bibliográficos
Autores principales: Anton, Lauren, DeVine, Ann, Sierra, Luz-Jeannette, Brown, Amy G., Elovitz, Michal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465080/
https://www.ncbi.nlm.nih.gov/pubmed/28596604
http://dx.doi.org/10.1038/s41598-017-03217-7