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High-dose maternal folic acid supplementation before conception impairs reversal learning in offspring mice
Maternal folic acid (FA) supplementation prior to and during gestation is recommended for the prevention of neural tube closure defects in the developing embryo. Prior studies, however, suggested that excessive FA supplementation during gestation can be associated with toxic effects on the developin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465191/ https://www.ncbi.nlm.nih.gov/pubmed/28596566 http://dx.doi.org/10.1038/s41598-017-03158-1 |