Mitochondrial biogenesis dysfunction and metabolic dysfunction from a novel mitochondrial tRNA(Met) 4467 C>A mutation in a Han Chinese family with maternally inherited hypertension

To investigate the relationship between mitochondrial DNA (mtDNA) and hypertension as well as the mechanism involved in mitochondrial metabolic dysfunction. We identified a novel tRNA(Met) C4467A mutation in a Han Chinese family with hypertension. The maternal members presented with increased glucos...

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Detalles Bibliográficos
Autores principales: Liu, Yuqi, Li, Yang, Zhu, Chao, Tian, Liuyang, Guan, Minxin, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465199/
https://www.ncbi.nlm.nih.gov/pubmed/28596595
http://dx.doi.org/10.1038/s41598-017-03303-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465199/
https://www.ncbi.nlm.nih.gov/pubmed/28596595
http://dx.doi.org/10.1038/s41598-017-03303-w

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