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Axin2-expressing cells differentiate into reparative odontoblasts via autocrine Wnt/β-catenin signaling in response to tooth damage

In non-growing teeth, such as mouse and human molars, primary odontoblasts are long-lived post-mitotic cells that secrete dentine throughout the life of the tooth. New odontoblast-like cells are only produced in response to a damage or trauma. Little is known about the molecular events that initiate...

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Detalles Bibliográficos
Autores principales: Babb, Rebecca, Chandrasekaran, Dhivya, Carvalho Moreno Neves, Vitor, Sharpe, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465208/
https://www.ncbi.nlm.nih.gov/pubmed/28596530
http://dx.doi.org/10.1038/s41598-017-03145-6