Cargando…
Microenvironmental cooperation promotes early spread and bistability of a Warburg-like phenotype
We introduce an in silico model for the initial spread of an aberrant phenotype with Warburg-like overflow metabolism within a healthy homeostatic tissue in contact with a nutrient reservoir (the blood), aimed at characterizing the role of the microenvironment for aberrant growth. Accounting for cel...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465218/ https://www.ncbi.nlm.nih.gov/pubmed/28596605 http://dx.doi.org/10.1038/s41598-017-03342-3 |