Leukocyte Bim deficiency does not impact atherogenesis in ldlr(−/−) mice, despite a pronounced induction of autoimmune inflammation

Proapoptotic Bcl-2 family member Bim is particularly relevant for deletion of autoreactive and activated T and B cells, implicating Bim in autoimmunity. As atherosclerosis is a chronic inflammatory process with features of autoimmune disease, we investigated the impact of hematopoietic Bim deficienc...

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Detalles Bibliográficos
Autores principales: Temmerman, Lieve, Westra, Marijke M., Bot, Ilze, van Vlijmen, Bart J. M., van Bree, Niek, Bot, Martine, Habets, Kim L. L., Keulers, Tom G. H., van der Vlag, Johan, Cotter, Thomas G., van Berkel, Theo J. C., Biessen, Erik A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465223/
https://www.ncbi.nlm.nih.gov/pubmed/28596542
http://dx.doi.org/10.1038/s41598-017-02771-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465223/
https://www.ncbi.nlm.nih.gov/pubmed/28596542
http://dx.doi.org/10.1038/s41598-017-02771-4

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