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Insulin Modulates Cytokine Release, Collagen and Mucus Secretion in Lung Remodeling of Allergic Diabetic Mice

INTRODUCTION: The role of insulin in lung remodeling in a model of asthma in healthy and diabetic mice was evaluated. MATERIAL AND METHODS: Diabetic male BALB/c mice (alloxan, 50 mg/kg, intravenous) and controls were sensitized by subcutaneous (s.c.) injection of ovalbumin (OA, 20 µg) in aluminum hy...

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Detalles Bibliográficos
Autores principales: Ferreira, Sabrina S., Nunes, Fernanda P. B., Casagrande, Felipe B., Martins, Joilson O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465276/
https://www.ncbi.nlm.nih.gov/pubmed/28649241
http://dx.doi.org/10.3389/fimmu.2017.00633