Deleterious Effects of Chronic Folate Deficiency in the Ts65Dn Mouse Model of Down Syndrome

Folate is an important B vitamin naturally found in the human diet and plays a critical role in methylation of nucleic acids. Indeed, abnormalities in this major epigenetic mechanism play a pivotal role in the pathogenesis of cognitive deficit and intellectual disability in humans. The most common c...

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Detalles Bibliográficos
Autores principales: Helm, Susan, Blayney, Morgan, Whited, Taylor, Noroozi, Mahjabin, Lin, Sen, Kern, Semira, Green, David, Salehi, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465284/
https://www.ncbi.nlm.nih.gov/pubmed/28649192
http://dx.doi.org/10.3389/fncel.2017.00161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465284/
https://www.ncbi.nlm.nih.gov/pubmed/28649192
http://dx.doi.org/10.3389/fncel.2017.00161

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