The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation

Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-associated molecular patterns by cytosolic sensory proteins to caspase-1 activation. Caspase-1 promotes pyroptotic cell death and the maturation and secretion of interleukin (IL)-1β and IL-18, which tr...

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Detalles Bibliográficos
Autores principales: Ratsimandresy, Rojo A., Chu, Lan H., Khare, Sonal, de Almeida, Lucia, Gangopadhyay, Anu, Indramohan, Mohanalaxmi, Misharin, Alexander V., Greaves, David R., Perlman, Harris, Dorfleutner, Andrea, Stehlik, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465353/
https://www.ncbi.nlm.nih.gov/pubmed/28580931
http://dx.doi.org/10.1038/ncomms15556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465353/
https://www.ncbi.nlm.nih.gov/pubmed/28580931
http://dx.doi.org/10.1038/ncomms15556

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