Neoadjuvant Hypofractionated Radiotherapy and Chemotherapy in High-Grade Extremity Soft Tissue Sarcomas: Phase 2 Clinical Trial Protocol

BACKGROUND: Neoadjuvant radiotherapy (RT) and chemotherapy are applied to large, high-grade extremity soft tissue sarcomas to treat metastatic disease earlier and sterilize margins to perform R0 surgery. However, preoperative RT increases wound complication rates (rWC), delaying adjuvant chemotherap...

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Detalles Bibliográficos
Autores principales: Spencer, Ranyell MSB, Aguiar Junior, Samuel, Ferreira, Fabio O, Stevanato Filho, Paulo R, Kupper, Bruna EC, Silva, Maria LG, Mello, Celso A, Bezerra, Tiago S, Lopes, Ademar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2017
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465377/
https://www.ncbi.nlm.nih.gov/pubmed/28546135
http://dx.doi.org/10.2196/resprot.6806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465377/
https://www.ncbi.nlm.nih.gov/pubmed/28546135
http://dx.doi.org/10.2196/resprot.6806

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