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T cells bearing anti-CD19 and/or anti-CD38 chimeric antigen receptors effectively abrogate primary double-hit lymphoma cells
Patients with B cell lymphomas bearing MYC translocation combined with translocation involving other genes, such as BCL2, BCL3, or BCL6, defined as double-hit lymphoma (DHL), have a poor prognosis. Recent studies expanded the concept to include double-expressing lymphoma (DEL) that co-overexpresses...
Autores principales: | Mihara, Keichiro, Yoshida, Tetsumi, Takei, Yoshifumi, Sasaki, Naomi, Takihara, Yoshihiro, Kuroda, Junya, Ichinohe, Tatsuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465447/ https://www.ncbi.nlm.nih.gov/pubmed/28595585 http://dx.doi.org/10.1186/s13045-017-0488-x |
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