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Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A

BACKGROUND: Hypericin-mediated photodynamic therapy (HY-PDT) has recently captured increased attention as an alternative minimally invasive anticancer treatment, although cancer cells may acquire resistance. Therefore, combination treatments may be necessary to enhance HY-PDT efficacy. Histone deace...

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Detalles Bibliográficos
Autores principales: Halaburková, Andrea, Jendželovský, Rastislav, Kovaľ, Ján, Herceg, Zdenko, Fedoročko, Peter, Ghantous, Akram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465463/
https://www.ncbi.nlm.nih.gov/pubmed/28603560
http://dx.doi.org/10.1186/s13148-017-0359-x