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Quantum mechanical/molecular mechanical and docking study of the novel analogues based on hybridization of common pharmacophores as potential anti-breast cancer agents

In an attempt to identify some new potential leads as anti-breast cancer agents, novel hybrid compounds were designed by molecular hybridization approach. These derivatives were structurally derived from hybrid benzofuran–imidazole and quinazolinone derivatives, which had shown good cytotoxicity aga...

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Detalles Bibliográficos
Autores principales: Asadi, Parvin, Khodarahmi, Ghadamali, Farrokhpour, Hossein, Hassanzadeh, Farshid, Saghaei, Lotfollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465832/
https://www.ncbi.nlm.nih.gov/pubmed/28626481
http://dx.doi.org/10.4103/1735-5362.207204