Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta

INTRODUCTION: Blood pressure is lower in females than males. Angiotensin II type-2 receptor (AT(2)R) induces vasodilation. This study determined whether sex differences in vascular AT(2)R expression occur and if androgens exert control on AT(2)R expression in the vasculature. METHODS: AT(2)Rs in the...

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Detalles Bibliográficos
Autores principales: Mishra, Jay S, Hankins, Gary D, Kumar, Sathish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465964/
https://www.ncbi.nlm.nih.gov/pubmed/27765882
http://dx.doi.org/10.1177/1470320316674875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465964/
https://www.ncbi.nlm.nih.gov/pubmed/27765882
http://dx.doi.org/10.1177/1470320316674875

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