Cargando…

Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta

INTRODUCTION: Blood pressure is lower in females than males. Angiotensin II type-2 receptor (AT(2)R) induces vasodilation. This study determined whether sex differences in vascular AT(2)R expression occur and if androgens exert control on AT(2)R expression in the vasculature. METHODS: AT(2)Rs in the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mishra, Jay S, Hankins, Gary D, Kumar, Sathish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465964/ https://www.ncbi.nlm.nih.gov/pubmed/27765882 http://dx.doi.org/10.1177/1470320316674875

Ejemplares similares

Prenatal Testosterone Exposure Decreases Aldosterone Production but Maintains Normal Plasma Volume and Increases Blood Pressure in Adult Female Rats
por: More, Amar S., et al.
Publicado: (2016)

Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity
por: Shan, HaiYan, et al.
Publicado: (2014)

Restoring Angiotensin Type 2 Receptor Function Reverses PFOS-Induced Vascular Hyper-Reactivity and Hypertension in Pregnancy
por: Dangudubiyyam, Sri Vidya, et al.
Publicado: (2023)

Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome
por: Qiu, Xintao, et al.
Publicado: (2022)

Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer’s Disease
por: Carr, Jessie S., et al.
Publicado: (2018)

Chemopreventive effects of angiotensin II receptor type 2 agonist on prostate carcinogenesis by the down-regulation of the androgen receptor
por: Ito, Yusuke, et al.
Publicado: (2018)

Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling()
por: Zaslavsky, Alexander B., et al.
Publicado: (2015)

Androgen receptor polymorphism, testosterone levels, and prognosis in patients with acute myocardial infarction
por: Wang, Anne, et al.
Publicado: (2021)

Testosterone Decreases Placental Mitochondrial Content and Cellular Bioenergetics
por: Mishra, Jay S., et al.
Publicado: (2020)

Cystatin C Is Downregulated in Prostate Cancer and Modulates Invasion of Prostate Cancer Cells via MAPK/Erk and Androgen Receptor Pathways
por: Wegiel, Barbara, et al.
Publicado: (2009)

Retraction: Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease
Publicado: (2019)

CRF(1) Receptor Signaling via the ERK1/2-MAP and Akt Kinase Cascades: Roles of Src, EGF Receptor, and PI3-Kinase Mechanisms
por: Parra-Mercado, G. Karina, et al.
Publicado: (2019)

ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
por: Buscà, Roser, et al.
Publicado: (2016)

Androgen receptors and serum testosterone levels identify different subsets of postmenopausal breast cancers
por: Secreto, Giorgio, et al.
Publicado: (2012)

Testosterone and Androgen Receptor Sensitivity in Relation to Hyperactivity Symptoms in Boys with Autism Spectrum Disorders
por: Pivovarciova, Anna, et al.
Publicado: (2016)

Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro
por: Roelofs, Maarke J.E., et al.
Publicado: (2014)

Testosterone Promotes Glioblastoma Cell Proliferation, Migration, and Invasion Through Androgen Receptor Activation
por: Rodríguez-Lozano, Dulce Carolina, et al.
Publicado: (2019)

SUN-LB138 Dynamic Structural Model of Testosterone Entry Into the Unliganded Androgen Receptor
por: Krylova, Irina, et al.
Publicado: (2020)

The role of testosterone, the androgen receptor, and hypothalamic-pituitary–gonadal axis in depression in ageing Men
por: Hauger, Richard L., et al.
Publicado: (2022)

Functional mapping of androgen receptor enhancer activity
por: Huang, Chia-Chi Flora, et al.
Publicado: (2021)

Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells
por: Vanshylla, Kanika, et al.
Publicado: (2018)

Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2
por: Perander, Maria, et al.
Publicado: (2017)

Identification of Androgen Receptor Metabolic Correlome Reveals the Repression of Ceramide Kinase by Androgens
por: Camacho, Laura, et al.
Publicado: (2021)

βKlotho inhibits androgen/androgen receptor-associated epithelial-mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling
por: Liu, Zhao, et al.
Publicado: (2018)

Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists
por: Vasile, Silvana, et al.
Publicado: (2020)

Prenatal Testosterone Exposure Leads to Gonadal Hormone-Dependent Hyperinsulinemia and Gonadal Hormone-Independent Glucose Intolerance in Adult Male Rat Offspring
por: More, Amar S., et al.
Publicado: (2015)

Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome
por: Zhou, Ruiqiong, et al.
Publicado: (2020)

Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells
por: LIU, TIANCHENG, et al.
Publicado: (2012)

Androgens downregulate miR-21 expression in breast cancer cells underlining the protective role of androgen receptor
por: Casaburi, Ivan, et al.
Publicado: (2016)

Gonadectomy reduces the density of androgen receptor-immunoreactive neurons in male rat’s hippocampus: testosterone replacement compensates it
por: Moghadami, Sajjad, et al.
Publicado: (2016)

Testosterone regulates keratin 33B expression in rat penis growth through androgen receptor signaling
por: Ma, Yan-Min, et al.
Publicado: (2014)

Size Matters: The CAG Repeat Length of the Androgen Receptor Gene, Testosterone, and Male Adolescent Depression Severity
por: Hirtz, Raphael, et al.
Publicado: (2021)

Casein Kinase 2 Dependent Phosphorylation of Neprilysin Regulates Receptor Tyrosine Kinase Signaling to Akt
por: Siepmann, Martin, et al.
Publicado: (2010)

Angiotensin Type 2 Receptors: Painful, or Not?
por: Pulakat, Lakshmi, et al.
Publicado: (2020)

Spred-2 Suppresses Aorta-Gonad-Mesonephros Hematopoiesis by Inhibiting MAP Kinase Activation
por: Nobuhisa, Ikuo, et al.
Publicado: (2004)

Receptors | Angiotensin Receptors
por: Pardhi, Triveni R., et al.
Publicado: (2021)

Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5α-Dihydrotestosterone and Androgen Receptor Binding
por: Dehghan, Firouzeh, et al.
Publicado: (2014)

Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen
por: De Silva, Dinuka, et al.
Publicado: (2019)

Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of β2-Adrenergic Receptor
por: Lee, Seon Jin, et al.
Publicado: (2018)

Estrogen Metabolite 2-Methoxyestradiol Attenuates Blood Pressure in Hypertensive Rats by Downregulating Angiotensin Type 1 Receptor
por: Zhang, Yong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i03usp0qh8f6p93appu4v5vjgs