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The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system
Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells using the manual patch clamp which requires s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466043/ https://www.ncbi.nlm.nih.gov/pubmed/28626710 http://dx.doi.org/10.1016/j.btre.2015.04.007 |