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The application of the Escherichia coli giant spheroplast for drug screening with automated planar patch clamp system

Kv2.1, the voltage-gated ion channel, is ubiquitously expressed in variety of tissues and dysfunction of this ion channel is responsible for multiple diseases. Electrophysiological properties of ion channels are so far characterized with eukaryotic cells using the manual patch clamp which requires s...

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Detalles Bibliográficos
Autores principales: Kikuchi, Kyoko, Sugiura, Mika, Nishizawa-Harada, Chizuko, Kimura, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466043/
https://www.ncbi.nlm.nih.gov/pubmed/28626710
http://dx.doi.org/10.1016/j.btre.2015.04.007

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