Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway

Several members of cucurbitaceae family have been reported to regulate growth of cancer by interfering with STAT3 signaling. In the present study, we investigated the unique role and molecular mechanism of cucurbitacins (Cucs) in reducing symptoms of metabolic syndrome in mice. Cucurbitacin E (CuE)...

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Detalles Bibliográficos
Autores principales: Murtaza, Munazza, Khan, Gulnaz, Aftab, Meha Fatima, Afridi, Shabbir Khan, Ghaffar, Safina, Ahmed, Ayaz, Hafizur, Rahman M., Waraich, Rizwana Sanaullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466318/
https://www.ncbi.nlm.nih.gov/pubmed/28598969
http://dx.doi.org/10.1371/journal.pone.0178910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466318/
https://www.ncbi.nlm.nih.gov/pubmed/28598969
http://dx.doi.org/10.1371/journal.pone.0178910

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