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The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress in osteosarcoma cells
Osteosarcoma (OS) is an aggressive bone malignancy commonly observed in children and adolescents. Sub-optimal therapy for years has irretrievably compromised the chances of OS patient survival; also, lack of extensive research on this rare disease has hindered therapeutic development. Cisplatin, a c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466322/ https://www.ncbi.nlm.nih.gov/pubmed/28598976 http://dx.doi.org/10.1371/journal.pone.0179203 |